The role of MRI in applying the 3Rs to non-human primate neuroscience

Magnetic resonance imaging is playing a significant role in applying the 3Rs to neuroscience studies using non-human primates. MRI scans are contributing refinement by enhancing selection and assignment of animals, guiding manufacture custom-fitted recording head fixation devices, assisting with diagnosis health issues their treatment. also being used better understand impact procedures on welfare NHPs. has helped optimise NHP use make greater scientific progress than would otherwise be made larger numbers animals. Whilst human fMRI have replaced some studies, potential directly replace electrophysiology limited at present. Given considerable advantages for experiments, including improved NHPs, consideration should given focusing laboratories around facilities. Greater sharing data sets, improvements contrast resolution, expected further advance future.